This notion was supported by an upregulation of ATF3 expression in human breast cancer [27], prostate cancer, Hodgkin’s lymphoma [28,29], lung cancer [30], and spontaneous multifocal keratinocyte tumors in mice carrying a mesenchymal-specific deletion of CSL/RBP-Jκ [31]. The gene discussed is RBPJ; the disease is prostate carcinoma.