IGF2 and Parkinson disease: Based on the above and given the solid association between PD and mild to moderate stress, the aim of this work was the study of the IGF-II neuroprotective effects against oxidative damage on a cellular combined model of PD and mild to moderate stress [17], based on corticosterone, an endocrine response marker to stress, and the dopaminergic neurotoxin 1-methyl-4-phenylpyridinium (MPP+).