Of note, both IL-8 and MIF have consistently been implicated in propagating inflammatory cascades in Inflammatory Bowel Disease (IBD) [33,34,35,36,37,38,39,40], Rheumatoid Arthritis (RA) [41,42,43,44,45,46], Systemic Lupus Erythematosus (SLE) [47,48,49]. This evidence concerns the gene MIF and inflammatory bowel disease.