Six were congenital cataracts, 10 patients were anterior-segment dysgenesis including PAX6-related phenotype, 48 were retinal dystrophy, and 85 were neuro-ophthalmic condition such as optic atrophy, albinism, or FRMD7-related infantile nystagmus (Figure 1B). The gene discussed is PAX6; the disease is Developmental cataract.