BRCA1 and ovarian cancer: Although all women in the United States should be mindful of their risk of developing breast/ovarian cancer and being a BRCA1/2 mutation carrier, women of Ashkenazi Jewish descent are at a significantly greater risk of carrying a deleterious the BRCA1/2 gene, compared to women of non-Ashkenazi Jewish backgrounds (1:40 vs. 1:500) [6].