MAPK3 and acute lymphoblastic leukemia: In summary, M. cordata has the potential to treat hoof diseases, where the therapeutic effects of the four main active substances, SAN, CHE, ALL, and PRO, are related to targets such as SRC, MAPK3, JAK2, and MTOR, and act through signaling pathways such as cAMP, JAK/STAT, PI3K-Akt, and Ras/MAPK.