Among other covariates tested as predictors of in-hospital death (Figure 2), age, chronic obstructive pulmonary disease (COPD), previous cardiac events, a decreased oxygen saturation level recorded at admission, baseline high white blood cell count, severe hypotension occurring during hospitalization, lymphocytopenia at baseline, reduced eGFR at admission, reduced PaO2/FIO2 ratio, and increased high-sensitivity CRP were associated with an increased risk of death (all p < 0.05, Figure 2). This evidence concerns the gene CRP and chronic obstructive pulmonary disease.