The current study demonstrated, for the first time, different levels of the highly glycosylated (HG) form of CD147 protein as well as the relevant glycosyltransferases (MGAT4a and MGAT5) across the three groups, with obese T2D participants having the highest levels, followed by obese non-diabetics. The gene discussed is MGAT4A; the disease is type 2 diabetes mellitus.