Furthermore, a 2–82% mutation rate among 36 ferroptosis associated genes (FRGs), including TP53, NFE2L2, FANCD2, DPP4, ALOX5, PTGS2, ALOX15B, ACSL4, CARS, and HMGCR, was detected in ccRCC in an analysis based on the GSCA database [108]. The gene discussed is CARS1; the disease is nonpapillary renal cell carcinoma.