As a result, the indicators of colitis, including decreased BW, shortened colon lengths, increased AUC of DAI scores, relative spleen weight, and histological scores (extent and regeneration), were alleviated in the APP + DSS group compared with the CAS + DSS group, indicating that APP intake suppressed experimental colitis induced by the above-mentioned procedure (Figure 1 and Figure 2). The gene discussed is APP; the disease is colitis.