Regarding the anti-obesity and lipid-lowering effects of 5-campestenone, it has been reported that it enhances hepatic β-oxidation related enzyme activity and mRNA expression through its ligand activity for PPARα, and consequently, it increases ketone body production, thereby inhibiting fatty acid biosynthesis [12,13]. This evidence concerns the gene PPARA and obesity due to melanocortin 4 receptor deficiency.