The application of CRGs (CRG1 and CRG3) after virus adsorption and penetration to cells (at 1 h post-infection) showed moderate replication inhibition against HSV-1 and ECHO-1 (average SI of 14) and slightly higher virus-inhibiting activity of CRG2 against these viruses (mean SI of ~23) (Table S2). Here, CXCL10 is linked to infection.