PVT1 and malignant colon neoplasm: This characteristic was demonstrated by a reduction in tumorigenic potency, especially when PVT1 was removed from colon cancer cells.[28]PVT1 has been reported to be associated with the oncogenic and tumor suppressor pathways in GC,[29] such as c-MYC,[15] FOMX1,[9] NOP2,[27] CCNB1, AURKB, STAT3/VEGFA,[16] and SKP2.