We observed that among 41 tested BrD family members, the correlation with cancer stemness across 27 tumor types was consistently positive or negative for only five and four BrD genes, respectively (namely ATAD2, BRD7, KAT2A, SMARCA4, TRIM28 [positive], and KAT2B, BAZ2B, SP100 and SMARCA2 [negative]). The gene discussed is TRIM28; the disease is cancer.