It is known that the ubiquitin E3 ligase CHIP interacts with and ubiquitinates c‐Myc, targeting c‐Myc for degradation by the 26S proteasome.[38] To determine whether CHIP was required for WBC100‐mediated c‐Myc ubiquitination in cancer cells, MOLM‐13 cells were treated with WBC100 for 4 h. The gene discussed is MYC; the disease is cancer.