On the contrary, other studies reported an association between low levels of IGF‐1 and conditions like CVD, diabetes mellitus, osteoporosis, and sarcopenia although a causal relationship has not been established (Brioche et al., 2014; Katsanos et al., 2001; Lenk et al., 2010; Saki et al., 2017). The gene discussed is IGF1; the disease is osteoporosis.