Using genetic variants as proxy for alcohol intake, the inverse associations between genotypes that predict lower alcohol consumption (ALDH2‐rs671 AA, ADH1B‐rs1229984 AA and AG) and IARC alcohol‐related cancers among men in CKB, especially UADT cancers, supported the causal effects of alcohol consumption on these cancers, as consistent with existing observational evidence.2, 5, 40. The gene discussed is ALDH2; the disease is cancer.