For ADH1B‐rs1229984, compared to men with GG genotype, men with AG or AA genotypes had 13% to 25% lower risks of overall cancer (0.87 [0.78‐0.96], AG vs GG; 0.84 [0.76‐0.93], AA vs GG) and IARC alcohol‐related cancers (0.80 [0.69‐0.93]; 0.75 [0.64‐0.87]), mainly driven by head and neck cancer (0.61 [0.39‐0.96]; 0.61 [0.39‐0.94]) and oesophageal cancer (0.68 [0.53‐0.88]; 0.60 [0.46‐0.78]; Figure 1B). This evidence concerns the gene ADH1B and cancer.