We detected recurrent KRAS p.G12V (n = 15/38) or p.G12R mutations (n = 12/38) in 27 out of 38 adenomatoid odontogenic tumors (71%) regardless of the age of the patient, tumor size, tumor location, follicular or extrafollicular variants, and fibrous capsule thickness [12]. This evidence concerns the gene KRAS and neoplasm.