SNAI1 and head and neck squamous cell carcinoma: • Involved in cell proliferation, migration, cisplatin resistance, and apoptosis inhibition in HNSCC cells [106, 133]. • Promotes the stemness and progression of oral cancer [107, 108]. • Stabilizes and induces Snail-dependent EMT in ACC [134]. • Associated with resistance to treatment and poor clinical outcomes with HNSCC patients [105].