NFKB1 and thyroid gland carcinoma: Thus, the finding that L-GILZ binds to NF-κB and prevents its nuclear translocation in undifferentiated thyroid cancer cells has led to the suggestion that the L-GILZ-mediated trapping of NF-κB in the cytoplasm contributes to the inhibition of proliferation induced by drugs targeting the MAPK transduction cascade [32].