The relevant studies have usually combined several inflammatory indicators, including CRP and interleukin-6, to evaluate disease activity without modeling (34–36), whereas we combined inflammation with nutrition-related indicators to build a model, not only improving clinical efficiency but also corroborating the new insight that nutrition-related factors are environmental triggers for development and modification of lifestyle-related chronic diseases, including IBD (37). The gene discussed is CRP; the disease is inflammatory bowel disease.