The predictive value of total IgE and blood eosinophil levels with regards to the therapeutic benefit of omalizumab in patients with allergic asthma has yet to be shown in previous studies, although we found that a blood eosinophil level of <300 cells/μL was predictive of an MCID in OCS sparing in the SAA patients (7, 19, 22). This evidence concerns the gene IGHE and allergic asthma.