Significant correlations were observed between SCG2 expression and T cell exhaustion (immune checkpoint genes), general T cells, CD8 + T cells, CD4 + T cells, Th1, Tfh, Th17, Monocyte, M1 macrophages, M2 macrophages, natural killer (NK) cell, dendritic cells, neutrophils in CRC. Here, SCG2 is linked to colorectal carcinoma.