IL1B and neuromuscular disease caused by qualitative or quantitative defects of dysferlin: IL-1β has also been implicated in muscle wasting disorders such as cancer cachexia (Graziano et al., 2005; Zhang et al., 2007; Deans et al., 2009; Suzuki et al., 2013; Fogelman et al., 2017), dysferlinopathy (Cohen et al., 2015; Hogarth et al., 2019) and Duchenne muscular dystrophy (Nagata et al., 2017).