BMPR1B and brachydactyly type A1: In addition, BMPR1b mutations were linked to Brachydactyly type A1 characterized by bones hyperplasia, indicating that BMPR1b alterations could affect both the HSCs and MSCs in different physiopathological contexts by affecting their response to BMP4 (Laperrousaz et al., 2013; Racacho et al., 2015).