(17) have investigated the role of CSCs in gastric adenocarcinoma using MKN-1 cells, which showed that CD71 (−) cells were more tumorigenic than CD71 (+) cells in the gastric adenosquamous carcinoma model and that most CD71 (−) cells were dormant (G1/G0 cell cycle phase) and resistant to 5-FU. The gene discussed is TFRC; the disease is gastric adenocarcinoma.