PRKCE and neoplasm: The expression of PKCε was much more downregulated in the advanced tumor stage (0.10 ± 5.8) and distant metastasis (0.08 ± 6.36) groups relative to the lower tumor stage group and the non-metastatic group, where its expression was reduced 0.05 ± 6.0- and 0.07 ± 5.87-fold, respectively.