Contrary to the immunohistochemistry expression of TIMP-1 in ovarian tumors, the concentration of TIMP-1, measured by ELISA, was much higher than the concentrations of TIMP-2 and TIMP-3 (***p>0.0001 vs TIMP-3; *p>0.05 vs TIMP-2) in the ascites of CN patients (Figure 6A). The gene discussed is TIMP3; the disease is ovarian neoplasm.