CD274 and neoplasm: High PD-L1 epithelial IRS showed significant association with large tumour size (p = 0.038), presence of perforation (p = 0.023), advanced pathologic T stage (p = 0.007), infiltrative TBC (p ˂ 0.0001), high TB score (p = 0.004), low TSR (p = 0.012) and absence of cap like peritumoural lymphocytic reaction (p = 0.036).