In this study, CD8+ T level was upregulated after autoimmune cell therapy, which has not been seen in other previous studies on the treatment of COPD, and the literature on autoimmune cell therapy of COPD is limited, so the reasons for the increase of CD8+ T level and the advantages and advantages of the increase of CD8+ T level on COPD still need to be further studied. The gene discussed is CD8A; the disease is chronic obstructive pulmonary disease.