Second, we compared the expression differences of m6A genes between unfavorable and favorable outcome NB groups and illustrated that ALKBH5, ZC3H13, METTL14, YTHDC1, HNRNPA2B1, METTL3, NHRNPC, RBMX, RBM15B, YTHDF1, IGF2BP1, RBM15, and IGF2BP3 are all differentially expressed (Figure 5). The gene discussed is METTL3; the disease is neuroblastoma.