CHD7 and isolated thyroid-stimulating hormone deficiency: Other CHD7-related symptoms included high arched palate (50%; 4/8), spinal malformation (25%; 2/8), digestive system dysfunction (25%; 2/8), secondary hypothyroidism (12.5%; 1/8), six fingers in the left hand (12.5%; 1/8), inguinal hernia (12.5%; 1/8), micrognathism (12.5%; 1/8), widened palpebral fissure (12.5%; 1/8), epicanthus (12.5%; 1/8), and short philtrum fish mouth (12.5%; 1/8).