Some of the 25 biomarkers, such as phospholipase B1 (PLB1) (33), discoidin receptor 2 (DDR2) (34), and psoriasis susceptibility 1 candidate 1(PSORS1C1) (35), have been identified as biomarkers and participate in the pathogenesis of RA. The gene discussed is PSORS1C1; the disease is rheumatoid arthritis.