CD274 and neoplasm: Moreover, in B16F10- and BRAF-mutated murine models, the group treated with cGAMP encapsulated into lipid nanoparticles conjugated with mannose (LP-cGAMP) and anti-programmed death-ligand 1 (PD-L1) exhibited a more long-lasting inhibition of tumor growth and achieved a more prolonged survival than others (107).