The data from GSE62165 showed that none of the six-FBXOs was associated with tumor location (N = 118) (Supplementary Figure S4A), while GSE21501 displayed that FBXO28 and FBXO32 were tightly linked to tumor size (N = 98); FBXO32 was also related to lymphatic metastasis (N = 101) (Figures 3A, B). Here, FBXO28 is linked to neoplasm.