Orthotopic pancreatic tumors in CD19Cre/+; Myd88Fl/Fl mice displayed trends towards decreased growth as compared to CD19+/+; Myd88Fl/Fl controls, but the change in growth was less robust than the tumor growth change displayed in MD4 mice (Figures 3A, 2B). This evidence concerns the gene CD19 and pancreatic neoplasm.