Interestingly, infected Lgals3–/– mice showed a drop in serum levels of Th1 and Th2 cytokines, including IFN-γ, IL-2, IL-5, IL-6, IL-10, and TNF, compared with WT mice; these differences were significantly pronounced at 14 days but ceased at 28 days post-infection. The gene discussed is LGALS3; the disease is infection.