Dunnigan syndrome (FPLD2), due to pathogenic variants in the LMNA gene encoding Type A lamins, is characterized by lipoatrophy of limbs and trunk with cushingoid features of face and neck, i.e. increased supraclavicular fat pads, double chin, buffalo hump, and with perineal accumulation of adipose tissue. Here, LMNA is linked to familial partial lipodystrophy, Dunnigan type.