Chen et al. (2016) have also reported the presence of a major population of IL-33+ cells among α-smooth muscle actin (α-SMA)+ interstitial myofibroblasts and a minor population among CD31+ peritubular vascular endothelial cells in the kidneys of unilateral ureteral obstruction (UUO) mice. In addition, IL-33 was constitutively expressed throughout the kidney in peritubular and periglomerular spaces of mice kidneys (Ferhat et al., 2018). This evidence concerns the gene IL33 and Ureteral obstruction.