Various immunomodulators are used for the treatment of respiratory diseases, including omalizumab, an anti-IgE antibody; benralizumab, mepolizumab, and reslizumab, IL-5 antibodies; and dupilumab, an IL-4 and IL-13 inhibitor monoclonal antibody which is used for the treatment of allergic asthma; some other antibodies are used for the treatment of other respiratory disorders such as lung infection and lung cancer (Desoubeaux et al., 2016). The gene discussed is IL4; the disease is respiratory system disorder.