DDX41 and Autoimmunity: In contrast, the detection of anti-glycine Abs, anti-GAD65 Abs, and tissue-based detection of hippocampal neuropil-targeting Abs most likely carry a higher chance of underlying autoimmunity; however, these patients were also considered as possible but not probable pAE cases because their specificity is still smaller than the “well-characterized” Abs described above [24–27].