EYA1 and hearing loss disorder: As EYA1 has roles in morphogenesis of the inner and middle ear structures10, it is logical to infer that P/LP variants in this gene will result in inner ear anomaly and mixed hearing loss, comprising simultaneous SNHL and conductive hearing loss; however, the prevalence of middle ear anomalies causing conductive hearing loss did not differ significantly between patients with and without P/LP variants.