Given that JMJD2C promotes colorectal cancer (CRC) metastasis via histone methylation of metastasis-related lung adenocarcinoma transcript 1 (MALAT1) [10], it is unclear whether and how JMJD2C-mediated downstream involving MALAT1 functions in NSCLC. The gene discussed is MALAT1; the disease is non-small cell lung carcinoma.