In the subgroups of gender (male or female), age (< 65 or ≥ 65 years), BMI (< 28 or ≥ 28 kg/m2), smoking history (no or yes), hypertension (no or yes), OHA at admission (no or yes), and insulin at admission (no or yes), there were no differences in the predictive power of GA in MACCEs (all P for interaction > 0.05). This evidence concerns the gene INS and Hypertension.