Levels of HNRNPA2B1 and IGFBP3 were higher in 66.7% (10/15, P < 0.05) and 40.0% (6/15, P > 0.05) of PCa tissues than in adjacent normal tissues, respectively, and the GS > 7 group exhibited elevated expression of HNRNPA2B1 and IGFBP3 compared with the GS < 7 group (both P < 0.05) (Fig. 2G). Here, IGFBP3 is linked to posterior cortical atrophy.