CD163 and COVID-19: Notably, both COVID-19 skin phenotypes—but not CLE—showed a marked upregulation of genes related to macrophage function, including macrophage receptors (CD209, CLU, MARCO, FCGR2A, CLEC5A, CD163, MRC1 and BST1), differentiation factors (IL32) and monocyte-recruiting chemokines (CXCL2 and CCL2) (Fig. 1a, Extended Data Fig. 2).