DHODH and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Namely, we showed that DHODH inhibition by TERI negatively regulates CA1 MFR set points and suppresses CA1 hyperexcitability in a genetic model of Dravet syndrome (Styr et al., 2019), one of the most intractable and severe forms of childhood epilepsy.