Although RET genomic alterations have been described in breast cancer (Paratala et al., 2018), results from independent studies, including our own, demonstrate that RET gene overexpression plays a key role in breast cancer pathogenesis and therapy response (Gattelli et al., 2020; Spanheimer et al., 2014; Varešlija et al., 2019). Here, RET is linked to breast carcinoma.