From densely connected glioma functional modules, we further predicted 12 potential Wnt/β‐catenin signalling pathway targeted genes, including AARSD1, HOXB5, ITGA6, LRRC71, MED19, MED24, METTL11B, SMARCB1, SMARCE1, TAF6L, TENT5A and ZNF281. The gene discussed is NTMT2; the disease is central nervous system cancer.