Of the common CRC driver mutations, APC (P = 0.0188), TP53 (P = 0.004), KRAS (P = 0.003) and FBXW7 (P = 0.024) were found more frequently mutated in low LN yield patients but did not reach statistical significance at multiple testing (Fig. 2a). Here, TP53 is linked to colorectal carcinoma.